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(CNN) — A defiant Republican Rep. Todd Akin of Missouri said Tuesday that he will stay in the Senate race to unseat Democrat Claire McCaskill despite mounting calls from across the political spectrum for him to withdraw over incendiary comments on rape and pregnancy.

Akin cited what he called a grassroots conservative movement in the country that needs a voice in government for his decision to reject increasing pressure from his own Republican Party, congressional colleagues and others to step aside.

“I’m in this race for the long haul and we’re going to win it,” Akin told conservative radio host Dana Loesch.

He spoke minutes after five past and present Republican senators from Missouri, including highly regarded figures like John Danforth and Christopher “Kit” Bond, added their voices to widespread calls for Akin to end his campaign.

“We do not believe it serves the national interest for Congressman Todd Akin to stay in this race,” said the statement by Sen. Roy Blunt and former senators Danforth, Bond, John Ashcroft and Jim Talent. “The issues at stake are too big, and this election is simply too important. The right decision is to step aside.”

Akin complained his detractors overreacted to a liberal media campaign to take him down. He said fellow Republicans “ran for cover at the first sound of gunfire.”

His decision means he faces the first statewide race of his career with no mainstream GOP backing. After he announced his intention to stay in the race, the National Republican Senatorial Committee made clear it would not provide any help.

“We continue to hope that Congressman Akin will do the right thing for the values he holds dear, but there should be no mistake — if he continues with this misguided campaign, it will be without the support and resources of the NRSC,” said a statement by communications director Brian Walsh.”

The political drama exposes the tension in the Republican Party created by the growth of the conservative movement, particularly the birth of the tea party movement before the 2010 mid-term elections.

A six-term congressman who won more than 60% support in his five reelection efforts, Akin is a staunch conservative Christian who opposes abortion. By staying in the race, Akin’s candidacy ensures the abortion issue will be a focal point of next week’s Republican National Convention.

Certain GOP presidential nominee Mitt Romney is basing his campaign on economic issues, and the attention to social issues such as abortion distracts from that message.

The controversy erupted after Akin told a television interview Sunday that a woman’s body is capable of preventing pregnancy in cases of “legitimate rape.” He later apologized, saying he was referring to “forcible rape” and acknowledged that women “do become pregnant” during such instances.

Romney’s campaign quickly distanced the candidate from Akin and declared that Romney didn’t oppose abortion in cases of rape.

However, the party platform being drafted ahead of next week’s convention includes an endorsement of a “human life amendment” to the Constitution that would outlaw abortion with no explicit exemption for rape or incest.

The language, approved by the platform committee on Tuesday, is similar to the platforms that were adopted by the party at its conventions in 2000, 2004 and 2008. Convention delegates are expected to approve the platform next week.

Romney told National Review Online on Monday that the comments by Akin were “insulting, inexcusable and, frankly, wrong.”

The issue is particularly sensitive for Romney’s running mate, Rep. Paul Ryan of Wisconsin, who is a devout Catholic opposed to abortion. The Romney campaign acknowledged that Ryan personally opposed abortion in cases of rape, but said Romney’s view was the policy of the ticket.

In a new ad and radio interviews Tuesday, Akin called his mistake a lone misstep with unintended consequences.

“Rape is an evil act; I used the wrong words in the wrong way. And for that, I apologize,” he said in the new ad that came out Tuesday. “As the father of two daughters, I want tough justice for predators, have a compassionate heart for the victims of sexual assault, and I pray for them. Fact is, rape could lead to pregnancy; the truth is rape has many victims. The mistake I made was in the words I said, not in the heart I hold. I ask for your forgiveness.”

He told the radio show of former Arkansas Gov. Mike Huckabee that “the defense of the unborn and a deep respect for life which underlie all of America — those are important parts of who we are and they are not things to run away from.”

Akin also characterized his mistake as isolated and relatively minor.

“Well it just seems that I just misspoke one word in one sentence on one day,” he told Huckabee. “I hadn’t done anything that was morally or ethically wrong, as sometimes people in politics do. … It does seem like a little bit of an overreaction.”

His decision won support from the Missouri Republican Assembly, which issued a statement urging the party to back Akin in the battle against McCaskill.

“The Republican leadership needs to grow a spine and disallow the Democrats, who always support their candidates even when they are wrong, to dictate our stance,” the group’s statement said. “… While Todd may have been indiscreet in his word choice, he was not wrong in his facts. Todd can win despite this misstep. All Republicans will lose if they continue throwing their candidates under the bus because of a poor word choice.”

However, top Republicans strengthened their calls for Akin to depart the race.

“In his heart of hearts, I’m certain that he is sincerely sorry for what he said, but in this instance, when the future of our country is at stake, sorry is not sufficient,” Senate Republican leader Mitch McConnell said in a statement. “To continue serving his country in the honorable way he has served throughout his career, it is time for Congressman Akin to step aside.”

American Crossroads, an influential conservative Super PAC, also cited the importance of the election, in which McCaskill’s seat is considered vital to GOP hopes of gaining a Senate majority.

“Rep. Akin faces a simple choice: Will he help Democrats hold the McCaskill seat and potentially the Senate majority by staying in the race, or will he help Republicans defeat Barack Obama’s most reliable ally in the Senate by getting out?” said Steven Law, the group’s president and CEO.

Nate Hodson, a spokesman for the Crossroads GPS non-profit that backs Republican candidates around the country, said the group won’t spend any more money in the Missouri Senate race for now.

Akin told Huckabee that a new poll showed him still ahead of McCaskill and that pundits had wrongly predicted he would lose in the GOP primary campaign that chose a Senate nominee for the November election.

“We have a message that people understand,” Akin said. “It isn’t something that’s in the brain. It’s in the heart.”

Under Missouri law, Akin would require a court order to pull out of the race if he waits beyond 6 p.m. ET on Tuesday.

Voters sounded split over the controversy in Akin’s U.S. House district, which comprises a broad swath of suburban St. Louis including formerly rural areas that have seen a large population increase in recent decades.

Gene Wood of St. Charles, about 20 miles west of St. Louis, said he voted for Akin in past elections and the recent Senate primary and still plans to support him.

“It strikes me that this is a tempest in a teapot,” Wood said, calling the issue “a matter of semantics.”

To Wood, “people are looking for something to accuse Todd or drag him down. … I don’t think he said anything that’s really worth all the coverage that it’s getting.”

Another St. Charles resident, Judi Meredith, owns a counseling business that deals with rape victims. She has not supported Akin in the past and said she was horrified by his comments.

“It really showed a level of lack of knowledge and ignorance about society and rape as it’s used against women as a tool of oppression,” Meredith said, adding she believes Akin should withdraw.

Opinion: Wake up — it’s not just Akin

If Akin stays in the race after the Tuesday night deadline, he must get a court order and pay for any necessary reprinting of ballots. The state Republican Party would choose another candidate to run against McCaskill, considered one of the most politically vulnerable senators in the country.

Democrats have sought to portray Akin’s stance on rape and abortion as indicative of the broader Republican approach to women’s issues.

President Barack Obama said Akin’s remarks were “offensive” and didn’t make sense, while House Democratic leader Nancy Pelosi called them “another manifestation of the total disregard and disrespect of women by Republican leaders.”

Empty chair on Piers Morgan after Akin cancels appearance

After previously criticizing Akin’s remarks, McCaskill issued more supportive comments later Monday.

“While I disagree with what he said, he has now in the last few hours really apologized for what he said,” McCaskill noted. “I think what is startling to me is that these party bigwigs are coming down on him and saying that he needs to kick sand in the face of the Republican primary voters.”

Amy Kremer, chairwoman of the Tea Party Express, said Tuesday that “the fact that Claire McCaskill wants him to stay in the race speaks volumes.”

She said the longer Akin remains in the race, the more his comments will overshadow crucial economic issues.

Akin’s remarks deemed ‘harmful’ to rape survivors

“What he said is completely indefensible and changes the narrative of what’s going on here,” Kremer said Tuesday on CNN’s “Starting Point with Soledad O’Brien.” “If he looks at the bigger picture, he will do what’s best and step aside.”

Akin asks for ‘forgiveness’ in new ad

Opinion: Pregnant by rape? Of course

Akin was one of the first members of Congress to join the Tea Party Caucus in 2010 and has easily won reelection in recent years. The lawmaker raised $2.2 million this cycle, as of July 18.

Before the new controversy, the top nonpartisan political handicappers had rated the Missouri race a “toss-up.”

Article Courtesy of CNN

NATIONAL: Politician Staying in Race Following Controversial Rape Comments  was originally published on